DNAPac RP Column >>了解產品規格及報價
Thermo DNA/RNA 核酸藥物分析管柱總覽
* Measured using a 20mer oligonucleotide
** Measured using a 25mer oligonucleotide
Thermo DNAPac RP 管柱的顆粒技術與優勢
DNAPac RP 採用IP-RP的分析模式，可同時高解析度的分析小片段與大片段的 DNA/RNA 核酸分子與藥物。適合搭配 LC/UV、LC/MS來分析。
Reverse phase (RP) column specifically for analysis of oligonucleotides and double stranded (ds) DNA and RNA fragments.
• Excellent MS compatibility
• Wide operating pH range: 0–14
• High temperature stability: up to 100°C
• High throughput
The DNAPac RP is a column designed for analysis of oligonucleotides and ds DNA and RNA fragments using LC/UV or LC/MS. The unique column chemistry provides excellent performance under a broad range of pH, temperature, and mobile phase compositions. In addition, the large pore size of the resin provides excellent separation of small to large oligonucleotides.
DNAPac RP 的發表論文:
(1) Moderna (默德納)於 Nature Communication (2021) 發表的文獻，使用 DNAPac RP 管柱分析長片段的核酸分子。
文獻連結: https://www.nature.com/articles/s41467-021-26926-0
(2) BNT 於 Journal of Pharmaceutical Sciences(2023)發表的文獻，使用 DNAPac RP 管柱分析BNT162b2 CoVid-19 mRNA。
文獻連結: https://www.sciencedirect.com/science/article/pii/S0022354923000096
(3) Thermo 於 Analytical Chemistry (2022) 發表的文獻，使用 DNAPac RP 與 Smart digest Rnase T1 kit 搭配質譜儀，進行 mRNA 的 sequencing mapping。